Author Archives: luciavazine

About luciavazine

PHARMA PROFESSIONAL, ITALY

Mom will teach you NMR

Originally posted on New Drug Approvals:
Dedicated to all moms in the world ETHYL PROPIONATE NMR, carbonyl is dad and oxygen mom, a methyl gets more attention ORIGINALLY IN http://orgspectroscopyint.blogspot.in/2014/07/ethyl-propionate-nmr-carbonyl-is-dad.html C=O group is dad O atom is mom Carbonyl is dad…

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TIDEGLUSIB ..An NSAID and neuroprotective agent.

Originally posted on New Drug Approvals:
Tideglusib M.Wt: 334.39 Formula: C19H14N2O2S CAS No.: 865854-05-3 4-Benzyl-2-(naphthalen-1-yl)-1,2,4-thiadiazolidine-3,5-dione Glycogen Synthase Kinase 3 beta (GSK-3beta; tau Protein Kinase I) Inhibitors Treatment of Neurologic Drugs (Miscellaneous) Alzheimer’s Dementia, Treatment ofCerebrovascular Diseases, NP031112; NP-031112, Nypta  Zentylor NP 031112 NP-12 NP031112…

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MIDAZOLAM …A short-acting hypnotic-sedative drug with anxiolytic and amnestic properties

Originally posted on New Drug Approvals:
MIDAZOLAM 8-chloro-6-(2-fluorophenyl)-1-methyl-4H-imidazo[1,5-a][1,4]benzodiazepine 59467-70-8 CAS NO OF FREE BASE 59467-94-6 MALEATE, Launched – 1982, Roche (Originator) 59467-96-8 (HCl) A short-acting hypnotic-sedative drug with anxiolytic and amnestic properties. It is used in dentistry, cardiac surgery, endoscopic procedures, as preanesthetic…

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TEGOBUVIR ..IN PHASE II FOR HEPATITIS C

Originally posted on New Drug Approvals:
TEGOBUVIR A non-structural protein 5B polymerase inhibitor for Treatment of chronic hepatitis C 5-[6-[2,4-Bis(trifluoromethyl)phenyl]pyridazin-3-ylmethyl]-2-(2-fluorophenyl)-5H-imidazo[4,5-c]pyridine CHEMICAL NAMES 1. 5H-Imidazo[4,5-c]pyridine, 5-[[6-[2,4-bis(trifluoromethyl)phenyl]-3-pyridazinyl]methyl]- 2-(2-fluorophenyl)- 2. 5-({6-[2,4-bis(trifluoromethyl)phenyl]pyridazin-3-yl}methyl)-2-(2-fluorophenyl)-5H- imidazo[4,5-c]pyridine MOLECULAR FORMULA C25H14F7N5 MOLECULAR WEIGHT 517.4 MANUFACTURER Gilead Sciences, Inc. CODE…

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DANOPREVIR (ITMN-191) …..a peptidomimetic inhibitor of the NS3/4A protease of hepatitis C virus (HCV)

Originally posted on New Drug Approvals:
Danoprevir Danoprevir(ITMN-191) is a peptidomimetic inhibitor of the NS3/4A protease of hepatitis C virus (HCV) with IC50 of 0.2-3.5 nM, inhibition effect for HCV genotypes 1A/1B/4/5/6 is ~10-fold higher than 2B/3A. Phase 2. Array…

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APREMILAST, … ORALLY ACTIVE PDE4 INHIBITOR

Originally posted on New Drug Approvals:
APREMILAST PDE4 inhibitor N-{2-[(1S)-1-(3-Ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl]-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl}acetamide (+)-2-[l-(3-ethoxy-4-methoxyphenyl)-2- methanesulfonylethyl]-4-acetylaminoisoindolin-l,3-dione, (S)—N-{2-[1-(3-ethoxy-4-methoxy-phenyl)-2-methanesulfonylethyl]-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl}acetamide (S)-N-{2-[1-(3-Ethoxy-4-methoxyphenyl)-2-methanesulfonylethyl]-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl}acetamide Molecular Formula: C22H24N2O7S   Molecular Weight: 460.50016 608141-41-9 CAS NO Celgene (Originator) CC-10004 (apremilast) is an oral compound that is being studied in multiple Phase III clinical trials for the…

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TEDIGLUTIDE ..Glucagon-like peptide 2 (GLP-2) analog; protects small intestinal stem cells from radiation damage.

Originally posted on New Drug Approvals:
TEDUGLUTIDE Glucagon-like peptide 2 (GLP-2) analog; protects small intestinal stem cells from radiation damage. Gattex (teduglutide) is a recombinant analog of human glucagon-like peptide 2 for the treatment of adults with short bowel syndrome.…

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